Profluent-AI/OpenCRISPR resource

Health v2 · maintenance only

Flags: no_releases no_license

Adoption not part of the score

1204 stars · 128 forks observed · 2026-08-28

What it is AI-extracted, prompt v1, taxonomy v1, 2026-08-30, confidence not recorded

OpenCRISPR is a collection of AI-designed gene editing systems released by Profluent Bio, including OpenCRISPR-1, a Cas9-like protein and guide RNA generated with protein language models. The repository distributes the protein sequences and license terms rather than executable software.

Use cases

• find an AI-designed Cas9 replacement for gene editing protocols
• download open gene editor protein sequences for research
• use a drop-in SpCas9 alternative with NGG PAM
• build base or prime editing systems with a novel nuclease
• study LLM-designed proteins for biotech applications

When to choose

• you need a freely licensed Cas9-like editor for research or commercial development
• you want to evaluate AI-generated gene editing proteins
• you need a nuclease compatible with canonical SpCas9 guide RNAs

When to avoid

• you expect runnable software, code, or pipelines - this is sequence data
• your jurisdiction or use case conflicts with the required license agreement
• you need a fully unrestricted open-source license without terms of use

Facets

dataset · maturity active

machine-learning llm-training data-generation bioinformatics artificial-intelligence healthcare cross-platform crispr gene-editing protein-design biotechnology synthetic-biology protein-sequences

Member repositories

For agents

markdown · JSON · MCP: product_card(name="Profluent-AI/OpenCRISPR")