# marbl/CHM13

The complete sequence of a human genome

Repository: https://github.com/marbl/CHM13
Canonical: https://ross.abutalabs.com/products/chm13
License: NOASSERTION
License Family: other
Last push: 2026-07-03T19:42:57+00:00

## Health v2 (maintenance only)
Score: 73/100 (v2, computed 2026-09-03T02:20:16.233290+00:00)
- activity 90, release rhythm 35, longevity 100
- inputs: {"age_days": 2743, "days_push": 61, "days_rel": null, "gap_med": null, "n_releases_24m": 0}
- flags: no_releases, no_license
- formula: round(0.45*activity + 0.35*rhythm + 0.20*longevity); archived -> min(score, 10)

## Adoption (not part of the score)
Stars 1054, forks 103 (observed 2026-08-28T04:03:24.110693+00:00)

## What it is
The Telomere-to-Telomere (T2T) consortium's complete telomere-to-telomere assembly of the CHM13hTERT human cell line, including the T2T-CHM13v2.0 release with a finished chromosome Y. The repository distributes assembly FASTA files, raw sequencing datasets (PacBio HiFi, Oxford Nanopore, 10X, BioNano, Hi-C), and UCSC genome browser hubs.

## Use cases
- download a complete telomere-to-telomere human reference genome
- get raw PacBio HiFi and Nanopore reads for the CHM13 cell line
- use T2T-CHM13 as a reference for read alignment and variant calling
- view the T2T assembly in the UCSC genome browser
- study human centromeres and repetitive regions missing from GRCh38
- access a complete human chromosome Y sequence

## When to choose
- you need the most complete human reference genome including repetitive and centromeric regions
- you want raw long-read sequencing data for the CHM13 cell line
- you are benchmarking assemblers or aligners against a gapless human reference

## When to avoid
- you need a clinical reference genome with broad annotation support - GRCh38 remains the standard
- you want software or analysis pipelines rather than data
- you need a diploid or diverse pangenome reference - consider the Human Pangenome Reference Consortium instead

## Facets
- artifact type: dataset
- maturity: stable
- function: data-generation
- domain: bioinformatics, healthcare
- platform: cross-platform
- tags: genomics, genome-assembly, telomere-to-telomere, reference-genome, human-genome, chm13, sequencing-data, bioinformatics

## Member repositories
- marbl/CHM13 (main) score 73

## Provenance
- Observed fields: from GitHub, fetched 2026-08-28T04:03:24.110693+00:00.
- Health v2: computed from the inputs above; adoption is never an input.
- Inferred fields (summary, facets, guidance): AI-extracted, prompt v1, taxonomy v1, on 2026-08-30T06:59:01.755479+00:00, confidence not recorded.
  - readme: https://github.com/marbl/CHM13 (fetched 2026-08-28T04:03:24.110693+00:00, sha 1da99b51b38b)
- Data as of 2026-08-30T08:39:29.467469+00:00.