# biopython/biopython

Official git repository for Biopython (originally converted from CVS)

Repository: https://github.com/biopython/biopython
Canonical: https://ross.abutalabs.com/products/biopython
Homepage: http://biopython.org/
Language: Python
License: NOASSERTION
License Family: other
Topics: python, bioinformatics, genomics, biopython, protein, protein-structure, sequence-alignment, phylogenetics, dna
Last push: 2026-08-20T15:46:25+00:00

## Health v2 (maintenance only)
Score: 76/100 (v2, computed 2026-09-03T02:20:16.233290+00:00)
- activity 98, release rhythm 35, longevity 100
- inputs: {"age_days": 6380, "days_push": 13, "days_rel": null, "gap_med": null, "n_releases_24m": 0}
- flags: no_releases, no_license
- formula: round(0.45*activity + 0.35*rhythm + 0.20*longevity); archived -> min(score, 10)

## Adoption (not part of the score)
Stars 5176, forks 1938 (observed 2026-08-28T04:09:11.749350+00:00)

## What it is
Biopython is a widely used open-source Python library of tools for computational molecular biology and bioinformatics. It provides modules for sequence input/output, alignment, BLAST, structural biology (PDB), phylogenetics, population genetics, and database interfaces like BioSQL and NCBI Entrez.

## Use cases
- parse fasta and genbank sequence files in python
- run pairwise or multiple sequence alignment
- query NCBI Entrez databases programmatically
- analyze protein structures from PDB files
- build phylogenetic trees from sequence data
- run BLAST searches and parse results
- work with DNA, RNA, and protein sequences

## When to choose
- you need a mature, well-documented Python toolkit for sequence analysis
- you want to parse common bioinformatics file formats (FASTA, GenBank, PDB, GFF)
- you need to interface with NCBI, BioSQL, or other biological databases from Python

## When to avoid
- you need high-performance genomics on massive datasets where specialized tools (e.g., pysam, GATK) fit better
- your work is outside computational biology
- you need a GUI application rather than a programming library

## Facets
- artifact type: library
- maturity: stable
- function: parser, data-science, sdk
- domain: bioinformatics, data-science
- platform: python, cross-platform
- tags: sequence-analysis, genomics, molecular-biology, blast, pdb, phylogenetics, sequence-alignment

## Member repositories
- biopython/biopython (main) score 76

## Provenance
- Observed fields: from GitHub, fetched 2026-08-28T04:09:11.749350+00:00.
- Health v2: computed from the inputs above; adoption is never an input.
- Inferred fields (summary, facets, guidance): AI-extracted, prompt v1, taxonomy v1, on 2026-08-29T18:01:49.530363+00:00, confidence not recorded.
  - readme: https://github.com/biopython/biopython (fetched 2026-08-28T04:09:11.749350+00:00, sha 7c831140dde6)
  - homepage: http://biopython.org/ (fetched 2026-08-29T08:55:52.040371+00:00, sha c8a2519e4f0e)
  - site_page: https://biopython.org/wiki/Documentation (fetched 2026-08-29T08:55:52.049521+00:00, sha d38f398589b9)
  - site_page: https://biopython.org/docs/latest (fetched 2026-08-29T08:55:52.051895+00:00, sha 6e5ddfc0e038)
  - site_page: https://biopython.org/wiki/Category%3AWiki_Documentation (fetched 2026-08-29T08:55:52.053730+00:00, sha 23839d44eae5)
- Data as of 2026-08-30T08:39:29.467469+00:00.